血清降钙素原对肝硬化并发自发性细菌性腹膜炎的诊断价值

目的]探讨血清降钙素原（PCT）对肝硬化并发自发性细菌性腹膜炎的诊断价值。方法]采用半定量固相免疫发光测量法测定17例肝硬化并发自发性细菌性腹膜炎患者血清PCT，免疫散射速率比浊法测定其血清C反应蛋白，常规方法检测外周血白细胞，同时与20例病毒性肝炎患者进行对照。结果]血清PCT对腹膜炎诊断的敏感性（17／17）和特异性（20／20）均为100％，敏感性优于外周血白细胞计数（23．5％，4／17）（P〈0．01），特异性优于C反应蛋白（5％，1／20）（P〈0．01）。结论]血清PCT测定对肝硬化并发自发性细菌性腹膜炎诊断有重要价值。

Diagonosis value of serum procalcitonin in cirrhotic patients with spontaneous bacterial peritonitis

Objective] To analyse initiatively the diagonosis of serum Procalcitonin(PCT) in cirrhotic patients with spontaneous bacterial peritonitis.Methods] Serum PCT were detected by semi-quantitative solid-phase immunoassay,CRP were measured by using immunity-turbidity method and white blood cells were counted by routine method from 17 cirrhotic patients with spontaneous bacterial peritonitis and compared with 20 viral hepatitis.Results] The sensitivity(17/17) and the specificity(20/20) of PCT were 100% for the diagnosis of patients with bacterial peritonitis.They were better than white blood cells(23.5%,4/17)(P<0.01) and CRP(5%,1/20)(P<0.01) respectively.Conclusions] The detection of PCT has an important value in diagnosis of cirrhotic patients with spontaneous bacterial peritonitis