双黄连注射液在生物体内抗细菌内毒素的效果观察

 目的：探讨双黄连注射液在生物体内抗细菌内毒素的效果。方法：观察双黄连注射液对内毒素休克小鼠的生存时间及对内毒素所致大鼠肝、肺、肾等病理改变的影响。用鲎试剂法测定双黄连注射液所致大鼠和人体血浆内毒素的含量变化。结果：双黄连注射液可明显降低动物和人体血浆内毒素含量，延长内毒素休克小鼠的平均生存时间，对内毒素所致大鼠的肝、肺、肾等损害具有保护作用。结论：双黄连注射液在生物体内具有显著的抗内毒素作用。

Effects on antibacterial endotoxin of Shuanghuanglian injection in living bodies

OBJECTIVE To investigate the effect of antibacterial endotoxin of Shuanghuanglian injection in living bodies.METHODS To observe the effect of Shuanghuanglian injection on the average death time of mice and the pathological changes of rats' livers , lungs and kidneys induced by endotoxin. The limulus test method was used to measure the changes of endotoxin concentration in plasma in rats and human bodies caused by Shuanghuanglian injection.RESULTS Shuanghuanglian injection can markedly decrease endotoxin concentration in plasma, lengthen the average death time of mice induced by endotoxin and protect the liver, lungs and kidneys of rats from endotoxin damage.CONCLUSIONS Shuanghuanglian injection has obvious effect on antiendotoxin in living bodies.