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| VEGF蛋白在子痫前期胎盘中的表达及意义 | |
| 引用本文： | 李芹,仇姝,王建军.VEGF蛋白在子痫前期胎盘中的表达及意义[J].河北医学,2010,16(10):1157-1160. |
| 作者姓名： | 李芹 仇姝 王建军 |
| 作者单位： | 1. 江苏省扬州环境资源职业技术学院医学系,江苏,扬州,225127 2. 江苏省扬州市妇幼保健院妇产科,江苏,扬州,225127 3. 扬州大学医学院形态实验室,江苏,扬州,225127 |
| 摘 要： | 目的：检测子痫前期胎盘的VEGF蛋白表达水平,探讨子痫前期的发病机制。方法：采用免疫组织化学方法结合病理图像分析技术,定量分析10例正常妊娠组、17例轻度子痫前期组和13例重度子痫前期组胎盘VEGF蛋白表达。结果：VEGF蛋白主要表达与胎盘绒毛滋养细胞的胞膜及胞浆内。与正常妊娠组比较,子痫前期组胎盘VEGF蛋白表达显著减少,轻度、重度子痫前期组比较,有显著性差异。结论：子痫前期患者胎盘滋养层细胞VEGF蛋白表达减少可能是子痫前期的发病机制之一,从而为临床治疗子痫前期提供新的方向。 |
| 关 键 词： | 血管内皮生长因子 子痫前期 胎盘 滋养层细胞 |
The Expression and Significance of VEGF in the Preeclampsia Placenta |
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| LI Qin,et al.The Expression and Significance of VEGF in the Preeclampsia Placenta[J].Hebei Medicine,2010,16(10):1157-1160. | |
| Authors: | LI Qin |
| Institution: | LI Qin,et al (Medical Department of Yangzhou Vocational College of Environment and Resources,Jiangsu Yangzhou 225127,China) |
| Abstract: | Objective: To detect expression of VEGF in placenta for the mechanism of the preeclampsia placenta.Method: Immunohistochemical staining method with pathological image analysis technology were taken to detect the expression of VEGF in 10 cases of normal pregnancy group,17 patients with mild preeclampsia and 13 patients with severe preeclampsia placentas.Result: Expression of VEGF mainly lies in placental trophoblast cells' membrane and the cytoplasm.With the normal pregnancy,expression of VEGF in placentas d... |
| Keywords: | Vascular endothelial growth factor(VEGF) Preeclampsia Placenta Trophoblast cells |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |