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骨骼肌卫星细胞生长因子与运动训练的关系
引用本文:谢永涛,蓝岚.骨骼肌卫星细胞生长因子与运动训练的关系[J].中国组织工程研究与临床康复,2011,15(37).
作者姓名:谢永涛  蓝岚
作者单位:1. 河北体育学院运动人体科学系,河北省石家庄市,050041
2. 保定学院生化系,河北省保定市,071000
摘    要:背景:大运动量训练可以导致骨骼肌组织微细结构的损伤性变化,而骨骼肌卫星细胞的激活、增殖与分化和肌肉组织损伤的修复有密切关系.目的:文章从训练导致肌肉组织结构性损伤需要修复的客观实际出发,提出运动后骨骼肌结构的修复与骨骼肌卫星细胞生长因子之间存在某种依赖关系.方法:由第一作者通过计算机网络检索中国期刊全文数据库(CNKI)和Medline数据库(2000/2010),检索词分别为"骨骼肌卫星细胞,生长因子,运动训练,骨骼肌超微结构"和"Skeletal muscle satellite cells,exercise,growth factor".共检索到97篇文章,按纳入和排除标准对文献进行筛选,共纳入23篇文章.从运动后骨骼肌组织修复与骨骼肌卫星细胞生长因子的激活作用机制进行总结,对两者间的联系进行分析.结果与结论:大强度训练可以导致骨骼肌组织的损伤,而卫星细胞是运动后恢复期骨骼肌修复的关键,其生长因子也与训练方式等因素有关.目前在骨骼肌卫星细胞的生长因子与运动训练之间的联系还缺乏足够的认识与研究.

关 键 词:骨骼肌卫星细胞  运动训练  生长因子  修复  组织工程

Relationship between skeletal muscle satellite cells and exercise
Xie Yong-tao,Lan Lan.Relationship between skeletal muscle satellite cells and exercise[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2011,15(37).
Authors:Xie Yong-tao  Lan Lan
Institution:Xie Yong-tao1,Lan Lan2 1Department of Human Sport Sciences,Hebei Institute of Physical Education,Shijiazhuang 050041,Hebei Province,China,2Department of Department of Biochemistry,College of Baoding,Baoding 071000
Abstract:BACKGROUND:High intensity of exercise can lead to injury to fine structure of skeletal muscle tissue, and the activation, proliferation and differentiation of skeletal muscle satellite cells are closely related to muscle tissue injury.OBJECTIVE:Based on the thinking that training can cause muscle structural damage and repair is needed, this study proposed a dependent relationship between repair of skeletal muscle structure and skeletal muscle satellite cells. METHODS:A computer-based retrieval was performed...
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