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夫妻活体供肾移植与血缘亲属供肾移植
引用本文:沈蓓莉,曲青山,杨磊,梁少峰,李明. 夫妻活体供肾移植与血缘亲属供肾移植[J]. 中国组织工程研究与临床康复, 2011, 15(31): 5777-5780. DOI: 10.3969/j.issn.1673-8225.2011.31.018
作者姓名:沈蓓莉  曲青山  杨磊  梁少峰  李明
作者单位:郑州人民医院器官移植科,河南省郑州市,450003
摘    要:背景:夫妻间活体肾移植尽管在组织配型方面差于血缘关系供肾移植,但在临床实践观察中夫妻肾移植与血缘关系肾移植间近期疗效并无明显差异。目的:对比同期实施的夫妻活体供肾移植和血缘亲属供肾移植的临床疗效,总结夫妻活体供肾移植的临床经验。方法:回顾性分析郑州人民医院实施的夫妻活体供肾移植18例及血缘亲属供肾移植100例的临床资料,通过对两组移植前组织配型情况和移植后(1,3,6个月)肾功能恢复情况,移植肾功能延迟恢及半年内急性排斥反应发生率、感染发生率等指标的分析,对夫妻活体供肾移植和血缘亲属供肾移植的临床疗效进行比较。结果与结论:同期进行的18例夫妻活体供肾移植组织配型情况较血缘关属供肾移植患者情况差。在移植方案及免疫抑制治疗方案相同的情况下,夫妻活体供肾移植后6个月内血肌酐恢复情况、术后移植肾功能延迟恢、急性排斥反应发生率、感染发生率,均与同期进行的血缘亲属活体供肾移植差异无显著性意义(P>0.05)。结果表明,无血缘关系的夫妻间供肾移植与血缘亲属供肾移植治疗效果相近。

关 键 词:夫妻  肾移植  活体供肾  血缘亲属  疗效

Living unrelated donor kidney transplantation between spouses and living related donor kidney transplantation
Shen Bei-li,Qu Qing-shan,Yang Lei,Liang Shao-feng,Li Ming. Living unrelated donor kidney transplantation between spouses and living related donor kidney transplantation[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2011, 15(31): 5777-5780. DOI: 10.3969/j.issn.1673-8225.2011.31.018
Authors:Shen Bei-li  Qu Qing-shan  Yang Lei  Liang Shao-feng  Li Ming
Affiliation:Department of Organ Transplantation, Zhengzhou People’s Hospital, Zhengzhou 450003, Henan Province, China
Abstract:BACKGROUND:Living unrelated donor kidney transplantation between spouses is poorer than living related donor kidney transplantation in tissue matching, but clinical practice shows that there is no obvious difference in short-term curative effects between these two types of kidney transplantation. OBJECTIVE:To compare the clinical curative effects between living unrelated donor kidney transplantation between spouses and living related donor kidney transplantation and summarize the clinical experience of kidn...
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