Calcium homeostasis disorder during and after neonatal extracorporeal membrane oxygenation |
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| Authors: | Jerome Rambaud Isabelle Guellec Julia Guilbert Pierre-Louis Léger Sylvain Renolleau |
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| Affiliation: | From: Paediatric Intensive Care Unit, Armand-Trousseau Hospital APHP (Paris Hospitals Public Assistance), UPMC (Pierre and Marie Curie University, Paris VI), Paris, France |
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| Abstract: | Results:During ECMO PTH was inadequately high with normal serum calcium on day 7 (PTH: 73.54 ± 40 ng/l; calcemia: 2.33 ± 0.21 mmol/l), day 14 (PTH: 57.63 ± 29.57 ng/l; calcemia: 2.44 ± 0.43 mmol/l) and day 21 (PTH: 54.93 ± 8.43 ng/l; calcemia: 2.13 ± 0.09 mmol/l). The absence of correlation between serum calcium and PTH levels seem to confirm the dysregulation of PTH - serum calcium metabolism during ECMO. Six months after ECMO weaning, we noticed hypercalcemia with normal PTH.Conclusions:We confirmed the existence of severe disturbances of calcium homeostasis in neonates on ECMO and supposed the possible damage of calcium regulation. We did not succeed in finding clear explanations of these disturbances. |
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| Keywords: | Calcium extracorporeal membrane oxygenation neonates parathyroid phosphorus |
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