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麦冬消渴胶囊和糖淤消胶囊微生物限度检查方法研究
引用本文:苑思坤,胡连栋,王庚南.麦冬消渴胶囊和糖淤消胶囊微生物限度检查方法研究[J].北方药学,2014,0(4):1-2.
作者姓名:苑思坤  胡连栋  王庚南
作者单位:河北大学 保定 071000;河北省保定市药品检验所 保定 071000;河北大学 保定 071000;河北农业大学 保定 071000
摘    要:目的:建立中成药麦冬消渴胶囊和糖淤消胶囊的微生物限度检查方法。方法:对5种阳性对照菌进行回收率试验以确定其检验方法。结果:回收率试验表明,麦冬消渴胶囊5种试验茵的回收率均高于70%,证明无抑菌现象;糖淤消胶囊对枯草芽孢杆菌有一定的抑菌作用,可用培养基稀释法消除其抑菌作用。结论:麦冬消渴胶囊可按常规方法进行微生物限度检查;糖淤消胶囊可按培养基稀释法进行微生物限度检查。

关 键 词:麦冬消渴胶囊  糖淤消胶囊  微生物限度  方法验证  抑菌作用

Validation Method Used for Microbial Limits of 2 Kinds of Traditional Chinese Medicine
Yuan Sikun Hu Liandong Wang Gengnan.Validation Method Used for Microbial Limits of 2 Kinds of Traditional Chinese Medicine[J].BEIFANG YAOXUE,2014,0(4):1-2.
Authors:Yuan Sikun Hu Liandong Wang Gengnan
Institution:Yuan Sikun Hu Liandong Wang Gengnan (1.Hebei University,071000;2.Baoding Institute for Drug Control,071000;3. Agricultural University of Hebei, 071000)
Abstract:Objective:To establish the method of microbial limit for 2 kinds of Traditional Chinese Medicine. Method:To determine the antimicrobial effect of 2 kinds of Traditional Chinese Medicine by recovery rate with 5 control trains. Results : According to the result, the recovery rates of Maidongxiaoke Capsule was higher than 70% ,which indicated no antimicrobial effect with them;Tangyuxiao Capsule had antimicrobial effects to some extend,the effect can be eliminated by dilution method. Conclusions:the resuhs suggested that common method be used for Maidongxiaoke Capsule, dilution method for Tangyuxiao Capsule.
Keywords:Microbial limit Validation Method Antimicrobial effect
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