丝裂霉素C预防浅表性膀胱癌等离子电切术后复发

目的探讨丝裂霉素C(MMC)预防浅表性膀胱癌等离子电切术(PKRBT)后复发的有效性。方法73例浅表性膀胱癌病人行PKBRT后即MMC 40 mg膀胱内灌注,常规MMC膀胱灌注12月。结果术后6月复发3例(4.1%),12月复发11例(15.1%),20月复发15例(20.5%)。结论MMC膀胱内灌注在PKRBT术后预防复发疗效良好。

Intravesical instillation of mitomycin C after transurethral plasmakinetic resection for the prophylaxis of superficial bladder cancer recurrence

Objective To evaluate the efficacy of intravesical instillation of mitomycin C after transurethral plasmakinetic resection for the prophylaxis of superficial bladder cancer recurrence.Method A total of 73 cases of superficial bladder cancer underwent transurethral plasmakinetic resection.All the cases were treated with intravesical instillation of 40 mg mitomycin C immediately after the operation.Regular intravesical instillation of mitomycin C has been given postoperatively to all cases for 1 year.All cases were followed up for 12 to 36 months(the mean is 24.6 months).Result There are 3,11,15 cases recurred at 6,12,20 months respectively.No serious side effect and complication developed either during or after instillation in all the cases.Conclusion Intravesical instillation of mitomycin C has been effective against recurrence of superficial bladder cancer after transurethral plasmakinetic resection,with advantages of good compliance and less systemic side effects.