| 玫瑰糠疹患者皮损中CD45RA与CD45RO的表达 |
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| 引用本文： | 张杰,钟绮丽,于波.玫瑰糠疹患者皮损中CD45RA与CD45RO的表达[J].实用诊断与治疗杂志,2007,21(5):341-342,I0001. |
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| 作者姓名： | 张杰 钟绮丽 于波 |
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| 作者单位： | 北京大学深圳医院皮肤科,广东省深圳市,518036 |
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| 摘 要： | 目的：观察玫瑰糠疹患者皮损中CD45RA与CD45RO的表达情况，探讨玫瑰糠疹的发病机制。方法：免疫组化SP法检测30例玫瑰糠疹患者皮损中CD45RA与CDRTRO的表达，取10例正常人躯干部皮肤作对照。结果：玫瑰糠疹患者皮损中CD45RO的表达明显高于正常对照组（P〈0．01），CD45RA的表达和正常对照组比较差异无统计学意义（P〉0．05）。结论：玫瑰糠疹患者皮损真皮中浸润的淋巴细胞以记忆性T淋巴细胞为主，推测细胞免疫在玫瑰糠疹的发病中起主要作用。
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| 关 键 词： | 玫瑰糠疹 |
| 文章编号： | 1672-3457（2007）05-341-02 |
| 收稿时间： | 2007-03-09 |
| 修稿时间： | 2007年3月9日 |
Expression of CD45RA and CD45RO in pityriasis rosea |
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| ZHANG Jie,ZHONG Qili,YU Bo.Expression of CD45RA and CD45RO in pityriasis rosea[J].Journal of Practical Diagnosis and Therapy,2007,21(5):341-342,I0001. |
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| Authors: | ZHANG Jie ZHONG Qili YU Bo |
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| Abstract: | Objective To investigate the expression of CD45RA and CD45RO in the lesions of pityriasis rosea. Methods The expression of CD45RA and CD45RO in the lesions of 30 pityriasis rosea were detected with immunohistochemical method and 10 cases of healthy skin were as control. Results The expression of CD45RO in pityriasis rosea lesion was higher than in healthy skin, but in CD45RA there was no statistic difference between the pityriasis rosea lesions and controls. Conclusion The lymphocytes in pityriasis rosea dermis are mainly memory lymphocytes. The cellular immunity plays a main role in the disease. |
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| Keywords: | CD45RA CD45RO |
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