IgA deficiency in children. Immunoglobulin-containing cells in the intestinal mucosa, immunoglobulins in secretions and serum IgA levels

Twenty-eight children with IgA deficiency were investigated by studying immunoglobulin-containing cells in the jejunal and rectal mucosa by direct immunofluorescence and by measuring immunoglobulins in the intestinal juice and saliva. Serum IgA was measured by radioactive single radial immunodiffusion.