| 红花煎剂直流电导入体外透皮实验研究 |
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| 引用本文： | 陈启蒙,杨金荣,张文英,李微.红花煎剂直流电导入体外透皮实验研究[J].中草药,1995,26(6):307-308. |
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| 作者姓名： | 陈启蒙 杨金荣 张文英 李微 |
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| 作者单位： | 天津医科大学药学系!300203 |
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| 摘 要： | 采用20mA直流电，以小鼠皮为模型膜，对红花水煎液直流电离子导入体外透皮实验。以薄层扫描法测定红花黄酮类药物透过量表明离子导入法促进红花黄酮类药物透皮吸收；药物导入置随离子导入时间的延长而增加，在实验条件下药物导入量不很大，可适当增加透皮面积。
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| 关 键 词： | 红花 直流电 透皮吸收 |
| 收稿时间： | 1994/11/8 0:00:00 |
Experimental Research of Iontophoresis with Decoction of Safflower (Carthamus tinctorius) |
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| Chen Qimeng,Yang Jinropg,Zhang Wenying.Experimental Research of Iontophoresis with Decoction of Safflower (Carthamus tinctorius)[J].Chinese Traditional and Herbal Drugs,1995,26(6):307-308. |
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| Authors: | Chen Qimeng Yang Jinropg Zhang Wenying |
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| Institution: | School of PHarmacy, Tianjin Medical Unviersity, Tianjin;School of PHarmacy, Tianjin Medical Unviersity, Tianjin;School of PHarmacy, Tianjin Medical Unviersity, Tianjin;School of PHarmacy, Tianjin Medical Unviersity, Tianjin |
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| Abstract: | This paper reported study on iontophrcsis of decoction of Carthamus tinctorius L. with rectified sin-electric current (current intensity 23 mA). The flavonoid of C. tinetorius was taken fer test index. The mouse skin was used as the analogue membrane. The drug amount of transdermal was determined by the TLC scanner.The results indicated that the effect of drug transdermal absorption was impreved by the experimental method of iontopheresis. The drug a mount of transdermal absorption increased with time prolong. |
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