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参麦注射液ADR数据库建立及流行病学特点研究
引用本文:吴新安.参麦注射液ADR数据库建立及流行病学特点研究[J].中国药房,2010(20):1878-1880.
作者姓名:吴新安
作者单位:解放军第105医院药剂科;
基金项目:南京军区医学科技创新课题项目(08MA045); 南京军区学科带头人培养对象培养计划项目(122工程)
摘    要:目的:探讨参麦注射液不良反应(ADR)的流行病学特点。方法:检索1990~2010年中文医药学期刊,收集参麦注射液ADR详细病案145例,应用ACCESS软件建立病案数据库,并依托数据库平台,对病案的流行病学资料进行统计、分析。结果:病案中,中老年患者比例最高(87.6%);男性55例(37.9%),女性90例(62.1%);原发疾病中,心血管疾病比例最高(62.1%);ADR以过敏性反应为主(38.0%),多发生在首次给药30min内(64.8%)。结论:建立参麦注射液ADR病案数据库,有助于更好地储存、分析病案信息,为临床参麦注射液ADR的预防和治疗提供参考。

关 键 词:参麦注射液  不良反应  数据库  流行病学

Establishment of Database and Study on Epidemiological Characteristics of ADR Caused by Shenmai Injection
WU Xin-an.Establishment of Database and Study on Epidemiological Characteristics of ADR Caused by Shenmai Injection[J].China Pharmacy,2010(20):1878-1880.
Authors:WU Xin-an
Institution:WU Xin-an(Dept.of Pharmacy,No.105 Hospital of PLA,Hefei 230031,China)
Abstract:OBJECTIVE:To investigate the epidemiological characteristics of adverse reaction(ADR) caused by Shenmai injection.METHODS:By retrieving from Chinese medical periodicals issued in 1990 to 2010,145 cases of ADR induced by Shenmai injection were collected to establish database using ACCESS.Based on established database,the epidemiological information was analyzed statistically.RESULTS:The incidence of ADR was the highest in the middle-aged and old sufferers(87.6%),and was 37.9% in the male(n=55) and 62.1% in t...
Keywords:Shenmai injection  ADR  Database  Epidemiology  
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