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复方中药对辐射小鼠细胞周期及免疫功能的影响
引用本文:徐书显,赵进沛,刘卫,王常有,张凤云,王忠海,赵娟,张茹珍.复方中药对辐射小鼠细胞周期及免疫功能的影响[J].现代中西医结合杂志,2001,10(7):609-610.
作者姓名:徐书显  赵进沛  刘卫  王常有  张凤云  王忠海  赵娟  张茹珍
作者单位:1. 中国人民解放军北京军区军事医学研究所,河北省石家庄市,050081
2. 河北医科大学生物教研室,石家庄市,050017
3. 河北省石家庄市第一人民医院药剂科,050011
基金项目:九五全军面上项目指令课题
摘    要:目的 :研究复方中药对辐射小鼠细胞周期及免疫功能的影响。方法 :应用流式细胞仪 (FCM)检测脾脏细胞周期和免疫参数 (NK,CD+4 ,CD+8)。结果 :该复方中药能使受照小鼠脾细胞 S,G2 + M期的比例升高 ,促进脾细胞增殖 ,并能提高N K细胞活性和 CD+4 百分率及 CD+4 / CD+8比值。结论 :复方中药对辐射损伤细胞具有一定的保护作用

关 键 词:复方中药  γ-射线辐射  细胞周期  免疫功能  流式细胞仪

Effect of compound Chinese herbal medicine on cell cycle and immune function of the mice with radiation
Xu Shuxian,Zhang Fengyun,Zhang Ruzhen,et al Military Medicine Institute of Chinese PLA,Shijiazhuang.Effect of compound Chinese herbal medicine on cell cycle and immune function of the mice with radiation[J].Modern Journal of Integrated Chinese Traditional and Western Medicine,2001,10(7):609-610.
Authors:Xu Shuxian  Zhang Fengyun  Zhang Ruzhen  Military Medicine Institute of Chinese PLA  Shijiazhuang
Institution:Xu Shuxian,Zhang Fengyun,Zhang Ruzhen,et al Military Medicine Institute of Chinese PLA,Shijiazhuang 050081
Abstract:Objective: It is to study the effect of the compound Chinese herbal medicine on the cell cycle and immune function of the mice with radiation.Methods: Cell cycle and immune parameter(NK, CD 4,CD 8)were detected in spleen with flow cytometry(FCM). Results: This compound Chinese herbal medicine can raised S,G 2 M phase ratio, promoted spleen cell proliferation, and can enhance vitality of NK cells and the percentage of CD 4 and CD 4 /CD 8 ratio. Conclusion: Compound Chinese herbal medicine have been protection action at cells radiation injury.
Keywords:compound Chinese herbal medicine  γ-ray irradiation  cell cycle  immune function  flow cytometry
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