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帕罗西汀与氟西汀治疗抑郁症的疗效比较
引用本文:赵彩云 赵焕华. 帕罗西汀与氟西汀治疗抑郁症的疗效比较[J]. 实用临床医学(江西), 2006, 7(11): 31-31,33
作者姓名:赵彩云 赵焕华
作者单位:常熟市第三人民医院,江苏常熟215500
摘    要:目的:评价国产帕罗西汀与氟西汀治疗抑郁症的临床效果和安全性。方法:将60例抑郁症病人随机分为两组:A组和B组.每组30例。A组采用国产帕罗西汀治疗;B组采用氟西汀治疗。两组均治疗6周。两组采用汉密尔顿抑郁量表(HAMD)评定疗效;用副反应量襄(TESS)评定副反应。结果:A组总有效率为76.7%,B组总有效率为80.0%,两组比较。差异无统计学意义(P〉0.05);两组治疗后HAMD评分均有明显下降(P均〈0.01)。结论:国产帕罗西汀与氟西汀治疗抑郁症疗效相当,且安全。

关 键 词:帕罗西汀 氟西汀 抑郁症 治疗
文章编号:1009-8194(2006)11-0031-01
收稿时间:2006-08-09
修稿时间:2006-08-09

A Comparative Trial of Domestic Paroxetine Versus Fluoxetine in the Treatment of Depression
ZHAO Cai-yun, ZHAO Huan-hua. A Comparative Trial of Domestic Paroxetine Versus Fluoxetine in the Treatment of Depression[J]. Practical Clinical Medicine, 2006, 7(11): 31-31,33
Authors:ZHAO Cai-yun   ZHAO Huan-hua
Abstract:Objective:To evaluate the efficacy and safety of Domestic Paroxetine and fluoxetine in the treatment of depression.Methods:Sixty patients with depression were randomly divided into two groups:Domestic Paroxetine group(30 cases)and fluoxetine group(30 cases)and all the patients were treated for 6 weeks.Hamilton Depression Scale(HAMD) was used for evaluating the therapeutic efficacy,while Treatment Emergent Symptom Scale(TESS)was for side effects.Results:There was no significant diference of efficacy between Domestic Paroxetine gronp and fluoxetine group.Conclusion:Domestic Paroxetine is an effective and safe agent in the treatment of depression.
Keywords:domestic paroxetine   fluoxetine   depression   treatment
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