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PDS型功能性消化不良患者胃排空研究
引用本文:张兰,李胜棉,姚树坤. PDS型功能性消化不良患者胃排空研究[J]. 河北医药, 2009, 31(19): 2545-2547
作者姓名:张兰  李胜棉  姚树坤
作者单位:河北医科大学第四医院消化内科,石家庄市,050011;北京中日友好医院
摘    要:目的研究餐后不适综合征(PDS)型功能性消化不良(FD)患者与健康人胃排空的差异。方法按照罗马Ⅲ诊断标准,选择PDS型FD患者34例纳入试验组,健康志愿者21例纳入对照组。对所有受试者进行核素胃排空检测,观察胃半排空时间(GET1/2)和120min胃排空率(GE120)。结果试验组GET1/2(106±26)min高于对照组GET1/2(78±14)min,2组间差异有统计学意义(t=5.066,P〈0.01);试验组GE120(56±13)min低于对照组GE120(71±11)min,2组间差异有统计学意义(t=-4.221,P〈0.01)。但是试验组症状积分与胃排空之间无相关性(P〉0.05)。结论PDS型FD患者较健康人易存在胃排空延迟。

关 键 词:功能性消化不良  餐后不适综合征  胃排空  核素  胃半排空时间  胃排空率

Gastric emptying parameters in post-prandial distress syndrome patients
ZHANG Lan,LI Shengmian,YAO Shukun. Gastric emptying parameters in post-prandial distress syndrome patients[J]. Hebei Medical Journal, 2009, 31(19): 2545-2547
Authors:ZHANG Lan  LI Shengmian  YAO Shukun
Affiliation:ZHANG Lan, LI Shengmian , YAO Shukun(Department of Digestion Diseases, The Fourth Hospital of Hebei Medical University, Shifiazhuang 050011 , China)
Abstract:Objective To investigate the difference of gastric emptying between the patients with post prandial distress syndrome (PDS) and healthy subjects. Methods According to Rome Ⅲ standard, 34 PDS patients in experiment group and 21 healthy subjects in control group were performed by gastric emptying. The gastric emptying half-time( GET1/2) and gastric emptying rate at 120 minutes (GE120 ) were detected as gastric emptying parameters. Results As compared with that in control group, the gastric emptying time was delayed significantly in experiment group,with GET1/2(min) of (106±26), as compared with (79±14) in control group (P〈0.01). As for GE120(% ) ,which was (56±13) in experiment group vs (71±12) in control group( P 〈 0.01 ). However as for PDS patients, there was no correlation between patients ' symptom scoring and gastric emptying rate ( P 〉 0.05). Conclusion As compared with healthy subjects,the patients with PDS are easier to have gastric dyskinesis.
Keywords:functional dyspepsia  post-prandial distress syndrome  gastric emptying  nuclide  gastric emptying half-time  gastric emptying rate
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