Danazol-Induced Cholestasis |
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| Authors: | Marcelo O Silva M D K Rajender Reddy M D Thomas McDonald M D Lennox J Jeffers M D Eugene R Schiff M D |
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| Institution: | Center for Liver Diseases, University of Miami School of Medicine, VA Medical Center, Florida. |
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| Abstract: | A 39-yr-old female on high-dose Danazol presented with jaundice and pruritus. Danazol-induced cholestasis was suspected, and the drug was discontinued. A liver biopsy revealed panlobular cholestasis with portal and periportal inflammation. The cholestasis resolved completely in 8 wk. This is a rare case of Danazol-induced cholestasis and should be considered in the differential diagnosis of drug-induced liver injury. |
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