传统换药与创面负压修复体表创面的结局比较

背景：尽管创面负压治疗技术已被广泛应用，但是大多数人只是基于临床经验或是主观判断认为创面负压治疗的优越性。目的：观察创面负压治疗体表创面的效果，并与同期传统治疗方法比较。方法：2006年1月至2011年12月北京协和医院收治的存在体表创面患者45例，其中25例患者应用负压治疗，20例患者应用传统换药治疗方法，记录相关治疗数据。结果与结论：创面负压治疗组在创面术前准备时间、肉芽生长速度、细菌的清除作用、工作人员劳动强度及术后并发症发生率方面均优于传统换药组（P 〈 0.05），但治疗费用差异无显著性意义（P 〉 0.05）。表明创面负压疗法相对于传统方法对创面的愈合起到了正性的促进作用，明显缩短了术前准备的时间，加速创面范围缩小，并降低了修复重建手术的并发症发生率，减轻患者痛苦及经济负担，降低了医务者的工作强度。创面负压治疗是从创面清创到进行修复重建手术这一中间期的有效治疗方式。

Outcomes of negative pressure wound therapy versus conventional dressing change in repair of wound on the body surface

BACKGROUND： Negative pressure wound therapy has been extensively used, but most people only knew the superiority of negative pressure wound therapy based on clinical experiences or subjective judgment.
OBJECTIVE： To observe the effects of negative pressure wound therapy on the wound on the body surface, and to compare with contemporaneous conventional method.
METHODS： A total of 45 patients with wound on the body surface treated in the Peking Union Medical College Hospital from January 2006 to December 2011 were enrolled in this study, including 25 patients undergoing negative pressure wound therapy and 20 patients undergoing conventional change dressing method. All clinical data were recorded.
RESULTS AND CONCLUSION： Negative pressure wound therapy was better than conventional method （P 〈 0.05）, on terms of preoperative preparation period, wound granulation, bacterial scavenging, labor intensity of working staff and incidence of postoperative complications. However, no significant difference in therapy cost was detectable （P 〉 0.05）. These results suggested that compared with conventional method, negative pressure wound therapy positively contributed to the healing, obviously shortened preoperative preparation, accelerated the diminution of wound, decreased the incidence of complications of reconstruction, lessened patient＇s distress, reduced their economic cost, and diminished labor intensity of working staff. Negative pressure wound therapy has been proven an excellent tool of to promote wound healing.