左氧氟沙星治疗老年社区获得性肺炎34例临床分析

目的探讨老年社区获得性肺炎（CAP）经验性治疗的最佳方案。方法选择老年CAP患者68例，随机分为左氧氟沙星组（治疗组）和头孢噻肟组（对照组）各34例，其中，左氧氟沙星组400mg每天一次静滴，头孢噻肟6g／a，分二次静滴，总疗程均为10-14天。结果治疗组有效率91％明显高于对照组的71％（P〈0.05），治疗组细菌清除率88％，也明显高于对照组的63％（P〈0.05）。结论左氧氟沙星400mg，每天一次静滴，治疗老年性CAP疗效好，不良反应轻，患者可以耐受，且一天一次给药，治疗方便、经济。

The clinical analysis of levofloxacin in the treatment of CAP elder patients of 34 cases

Objective To explore the best way of community-acquired peneumonia（CAP） elder patients. Methods There were 68 cases of CAP elder patients who were divided into groups with 34 cases for each at random. Levofloxacin and cefotaxime sodium was administration to another. The whole process last for 10-14 days, with the administration of levofloxacin 400 mg oncdaily, and cefotaxime sodium 3.0 g twice-daily. Results The total effective rates and bacterial eradication rates were obviously higher than that of control group （91% to71% P〈0.05,88% to 63% P〈0.05）.Conclusions The regimen of levofloxacin 400 mg once-daily is more effective than cefotaxime sodium 3.0 g twice-daily in the treatment of CAP elder patients, and it is an economic treatment method, and the advere effects are slight and tolerable.