抗心磷脂抗体与各类流产的关系

目的 :探讨抗心磷脂抗体 (ACA)与流产的关系。方法 :对 80例正常初孕妇 (对照组 )和 93例流产孕妇(流产组 ,其中先兆流产 6 2例 ,难免流产 2 1例 ,过期流产 10例 )采用酶联免疫吸附法测定血清抗心磷脂抗体IgM。结果 :①流产组ACA阳性率明显高于对照组 (P <0 .0 5 )。②有流产史者较无流产史ACA阳性率明显增高 (P <0 .0 5 ) ,习惯性流产史与非习惯性流产史间ACA阳性率差异无显著性 (P >0 .0 5 )。结论 :ACA阳性可能与自然流产有关 ,但ACA阳性与是否习惯性流产无明显关系

Relationship between anticardiolipin antibodies and abortion

Objective To explore the relationship between anticardiolipin antibodies (ACA) and abortion. Methods The level of serum ACA in 93 abortion women (abortion group) and 80 normal pregnant women (control group) was determined by the enzyme linked immunoabsorbent assay. The abortion group included threatened abortion (n=62), inevitable abortion (n=21), and missed abortion (n=10). Results The positive rate of ACA in the abortion group was significantly higher than that in the control group (P<0.05). The positive rate of ACA in pregnant women with a history of abortion was significantly higher than that in those women without a history of abortion (P<0.05). The positive rate of ACA was not significantly different between habitual abortion and spontaneous abortion (P>0.05). Conclusion Anticardiolipin antibodies may induce abortion, but it is not related to habitual aboriton.