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Anorexia nervosa, osteoporosis and circulating leptin: the missing link
Authors:I. Legroux-Gérot  J. Vignau  E. Biver  P. Pigny  F. Collier  X. Marchandise  B. Duquesnoy  B. Cortet
Affiliation:1. Department of Rheumatology, University of Lille II, 59037, Lille Cédex, France
2. Department of Addictology, University of Lille II, 59037, Lille Cédex, France
3. Department of Biology, University of Lille II, 59037, Lille Cédex, France
4. Department of Gynaecology, University of Lille II, 59037, Lille Cédex, France
5. Department of Nuclear Medicine, University of Lille II, 59037, Lille Cédex, France
Abstract:

Summary  

Methods: Leptin levels were measured in 103 consecutive women with anorexia nervosa. Results: Spine BMD and Z-score values were found to be significantly lower in the low tertile compared with the highest tertile. Duration of amenorrhea and leptin level accounted for 27% of the variance in lumbar spine BMD.
Keywords:
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