卡介菌多糖核酸预防尖锐湿疣复发的疗效观察

目的：观察卡介菌多糖核酸预防尖锐湿疣（CA）复发的疗效。方法：136例CA患者，在所有CA皮损用CO2激光一次性清除后，治疗组采用肌肉注射卡介菌多糖核酸1mlqod，36d为一疗程。一疗程结束后停药半月，再用一疗程。对照组仅用CO2激光治疗。术后3个月评定疗效。结果：治疗组复发率为7．04％，对照组复发率为21．54％，两组复发率比较有显著性差异（x2=4．84，P〈0．05）。结论：CO2激光结合卡介菌多糖核酸治疗可减少CA的复发，值得临床推广应用。

Effect of Bacillus Caimette-Guerin on the prevention against reoccurrence of condyloma acuminatum

Objectives： To observe the effect of Bacillus Caimette - Guer on the preventing against reoccurrence of condylo- ma acuminatum（CA）. Methods： A total of 136 cases were administered with CO2 Laser in their CA lesion. The treatment group were provided with Bacillus Caimette - Guer （ 1ml,im qod ×72day） treatment for 36 days, and then followed by the second treat- ment course after half a month medication pause. The control group was only provided with CO2 Laser treatment. The therapeutic effects were evaluated after 3 months. Results： The rate of the treatment group was 7.04% as compared to the rate of 21.54% in the control group, their differences being significant （x22 = 4. 84, P 〈 0.05 ）. Conclusion： CO2 Laser treatment combined with Bacillus Caimette - Guer can significantly reduce the risk of CA reoccurence.