One year's experience with recombinant erythropoietin in children undergoing continuous ambulatory or cycling peritoneal dialysis |
| |
| Authors: | Gisela Offner Peter F Hoyer Kay Latta Lothar Winkler Johannes Brodehl Paul Scigalla |
| |
| Institution: | (1) Department of Paediatric Nephrology and Metabolic Disorders, Childrens Hospital Medical School, Hannover, Federal Republic of Germany;(2) Boehringer Mannheim GmbH, Mannheim, Federal Republic of Germany;(3) Kinderklinik der Medizinischen Hochschule Hannover, Konstanty Gutschow Strasse 8, D-3000 Hannover, Federal Republic of Germany |
| |
| Abstract: | Fourteen patients (aged 5.9–22.1 years) undergoing continuous ambulatory or cycling peritoneal dialysis were treated with recombinant human erythropoietin (rhEPO), which was given intravenously once a week at a dosage of 300 units/kg. The mean haematocrit level increased from 18.5% to 27.5% and the reticulocyte count from 19 to 62 within 1 month. After an average time of 3.1 months rhEPO dosage could be adjusted to 100 units/kg per week to keep the haematocrit level at 30%. Only 1 patient had an exacerbation of hypertension, which required a dosage reduction; other side-effects were not noted. |
| |
| Keywords: | Recombinant human erythropoietin Continuous ambulatory peritoneal dialysis Continuous cycling peritoneal dialysis Renal anaemia |
| 本文献已被 SpringerLink 等数据库收录！ |
