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Studies of reservoir hosts for Marburg virus
Authors:Swanepoel Robert,Smit Sheilagh B,Rollin Pierre E,Formenty Pierre,Leman Patricia A,Kemp Alan,Burt Felicity J,Grobbelaar Antoinette A,Croft Janice,Bausch Daniel G,Zeller Hervé,Leirs Herwig,Braack L E O,Libande Modeste L,Zaki Sherif,Nichol Stuart T,Ksiazek Thomas G,Paweska Janusz T  International Scientific  Technical Committee for Marburg Hemorrhagic Fever Control in the Democratic Republic of Congo
Affiliation:National Institute for Communicable Diseases, Sandringham, Republic of South Africa. bobs@nicd.ac.za
Abstract:To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998-2000. We found MARV nucleic acid in 12 bats, comprising 3.0%-3.6% of 2 species of insectivorous bat and 1 species of fruit bat. We found antibody to the virus in the serum of 9.7% of 1 of the insectivorous species and in 20.5% of the fruit bat species, but attempts to isolate virus were unsuccessful.
Keywords:Marburg virus   reservoir hosts   research
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