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早孕绒毛产前诊断的研究
引用本文:马庭元,闻良珍,凌霞珍,任景慧,钟晓燕,付丽敏,朱继望. 早孕绒毛产前诊断的研究[J]. 华中科技大学学报(医学版), 1988, 0(1)
作者姓名:马庭元  闻良珍  凌霞珍  任景慧  钟晓燕  付丽敏  朱继望
作者单位:同济医科大学附属同济医院妇产科(马庭元,闻良珍,凌霞珍,任景慧),同济医科大学计划生育研究所(钟晓燕,付丽敏),同济医科大学计划生育研究所(朱继望)
摘    要:用早孕绒毛进行产前诊断正日益广泛开展。本文通过培养基加用Hepes液后,明显提高了分裂相出现率及可供分析率。用1%低渗构橼酸钠液,改善了染色体形态和分散状态。提出绒毛取材时间以孕6~7周最适宜。对10例染色体病风险急者做了产前诊断,认为孕早期绒毛产前诊断是可行、准确和安全的。

关 键 词:早孕绒毛  产前诊断  优生

A Study of Prenatal Diagnosis with Chorionic Villus in Early Pregnancy
Ma Tingyuan,Wen Liangzhen,Ling Xiazhen,Ren Ginghui. A Study of Prenatal Diagnosis with Chorionic Villus in Early Pregnancy[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1988, 0(1)
Authors:Ma Tingyuan  Wen Liangzhen  Ling Xiazhen  Ren Ginghui
Affiliation:Ma Tingyuan,Wen Liangzhen,Ling Xiazhen,Ren GinghuiDepartment of Obstetrics and Gynecology,Tongji Hospital,Tcngji Medical University,WuhanZhong Xiaoyan,Fu Liming,Zhu Giwang Institute o} Family Planning,Tongji Medical University,Wuhan
Abstract:Prenatal diagnosis by chorionic villi sampling is being extensively developed. In this paper, after the addition of Hepes to the medium, the occurrence and analysable rates of mitotic phases are apparently increased. The 1% sodium citrate solution has been proved to be favourable in the improvement of morphological figures and dispersion of chromosomes. The time for sampling is suggested between 6-7 gestation weeks. Prenatal diagnosis has been carried out in 10 cases with suspected hereditary chromosomal diseases. Through preliminary observation of prenatal diagnosis by chorionic villi sampling in early pregnancy, the method is useful, accurate and safe, which will show a wide prospect for further carrying on works of eugenics and family planning.
Keywords:chorionic villus of early pregnancy  prenatal diagnosis  eugenics
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