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模拟失重对心血管功能的影响及下体负压的对抗作用
引用本文:孙喜庆,姜世忠,姚永杰,蒋昌林,郝卫亚,吴兴裕.模拟失重对心血管功能的影响及下体负压的对抗作用[J].航天医学与医学工程,2002,15(4):236-240.
作者姓名:孙喜庆  姜世忠  姚永杰  蒋昌林  郝卫亚  吴兴裕
作者单位:1. 第四军医大学航空航天医学系,陕西西安,710032
2. 航天医学工程研究所,北京,100094
摘    要:总结了近年来本实验室有关模拟失重对心血管功能影响及下体负压对抗作用的研究,讨论了模拟失重致立位耐力不良的机理可能与心血管功能降低,脑血流降低及内分泌改变等有关,以及采用数学模型方法探讨失重致立位耐力降低机制的作用意义,重点论述了下体负压对抗方案问题。

关 键 词:模拟失重  心血管功能  下体负压  对抗作用  失重模拟  卧床试验  数学模型
文章编号:1002-0837(2002)04-0235-06
修稿时间:2001年8月26日

Effects of Simulated Microgravity on Cardiovascular Function and Counter Effect of Lower Body Negative Pressure
Xi-qing Sun,Shi-zhong Jiang,Yong-jie Yao,Chang-lin Jiang,Wei-ya Hao,Xing-yu Wu.Effects of Simulated Microgravity on Cardiovascular Function and Counter Effect of Lower Body Negative Pressure[J].Space Medicine & Medical Engineering,2002,15(4):236-240.
Authors:Xi-qing Sun  Shi-zhong Jiang  Yong-jie Yao  Chang-lin Jiang  Wei-ya Hao  Xing-yu Wu
Institution:Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, The Fourth Military Medical University, Xi'an, China. sunxiqing@163.net
Abstract:Studies on effect of simulated microgravity on cardiovascular function and counter effect of lower body negative pressure(LBNP) in recent years were summarized. The mechanism of simulated microgravity induced orthostatic intolerance may involve the reduction of cardiovascular function and cerebral blood flow, and endocrine changes. The significance of mathematical model in the study of mechanism of microgravity induced orthostatic intolerance was also discussed. The counter effect of LBNP was emphasized.
Keywords:weightlessness simulation  bed rest(tests)  orthostatic tolerance  lower body negative pressure  cardiac function  mathematical model
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