频域前节OCT对LASIK术后保留角膜基质床厚度测量的观察

目的：观察使用频域前节OCT测量准分子激光原位角膜磨镶术（LASIK）术后保留角膜基质床厚度的临床意义.方法：使用Moria 90 μm（A组）一次性刀头和Moria 110 μm可重复使用刀头（B组）制作板层角膜瓣行LASIK治疗各50例共200眼,术中用A超的方法测量计算保留角膜基质床厚度,术后用频域前节光学相干断层成像术（OCT）测量保留角膜基础床厚度.结果：用A超的方法测得保留角膜基质床厚度为A组304±1μm,B组292±18μm,OCT测量保留角膜基础床厚度为A组332±15μm,B组325±18μm.用90μm一次性刀头 所制的角膜瓣厚度为131.3±12.8μm,用110μm刀头制作的角膜瓣厚度为180.1±12.8μm.结论：频域前节OCT能比较准确测量LASIK术后保留角膜基质床厚度.用90μm和110μm刀头所制作的角膜瓣厚度与标记的厚度存在较大的误差,分别相差约50μm和80μm.

Observation of Measurement for Post-LASIK Residual Corneal Stromal Bed Thickness Using Frequency-domain Anterior Segment OCT

Objective： To observe the clinical significance of measurement for residual corneal stromal thickness using the frequency-domain anterior segment optical coherence tomography （OCT）. Methods： One hundred cases （200 eyes） who received LASIK were divided into two equal groups of 50 cases （100 eyes）. The corneal flap was created using the disposable Moria M2 90-micron head in the group A and the reusable Moria M2 110-micron head in the group B. The residual corneal stromal bed thickness was measured with A-scan uhrasonography intraoperatively and with frequency-domain anterior segment OCT postoperatively. Results：The residual corneal stromal bed thickness measured with A-scan uhrasonography was 304±1μm in group A and 292 ±18μm in group B. However, with the OCT, the residual corneal stromal bed thickness was 332 ±15μm in group A and 325 ±18μm in group B. The mean corneal flap thickness was 131.3 ±12.8μm and 180. 1 ±12.8μm with the 90 micron head and 110 micron head, respectively. Conclusion： Frequency-domain anterior segment OCT can measure post-lasik residual corneal stromal thickness relatively accurate. Big errors occurred between the corneal flap thicknesses created by 90 micron head and 110 micron head and tagged corresponding thickness; the errors were about 50μm and 80μm, respectively.