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A noninvasive tissue reflectance oximeter
Authors:Setsuo Takatani  Peter W Cheung  Edward A Ernst
Institution:(1) Department of Artificial Organs, Cleveland Clinic Foundation, 9500 Euclid Ave., 44106 Cleveland, Ohio;(2) Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio;(3) Department of Anesthesiology, The University of Alabama, Birmingham, Alabama
Abstract:A newly developed noninvasive tissue reflectance oximeter utilizes 5 light emitting diodes operating at the wavelengths of 0.635, 0.665, 0.795, 0.910, and 0.955 μ, and photodiodes to sample the tissue reflectance spectra. Since the tissue reflectance is affected by changes in both hemoglobin content (Hb T) and hemoglobin oxygen saturation (OS T),Hb T is first determined using the reflectance at 0.795 μ. The hemoglobinOS T is then estimated using the reflectances at the 5 wavelengths in conjunction with the diffuse reflectance equation which has previously been verified applicable to tissue reflectance oximetry. A quantitative estimation of bothHb T andOS T in intestinal mucosa of dogs obtained using this instrument showed thatHb T values agreed fairly well with those of others and that the standard errors ofOS T were around 5.0% inOS as compared with theOS values of blood samples for minimized arterial-venousOS differences. The continuous on-line measurement ofHb T andOS T should be possible using the reflectance technique and should be valuable for clinical evaluation of the patients.
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