Spectral data analyses and structure elucidation of metoprolol tartrate |
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Authors: | Qiao Jun-qin Wang Ya-qin Liu Chen-chen Zhu Wei Lian Hong-zhen Ge Xin |
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Institution: | Center of Materials Analysis, Key Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), School of Chemistry & Chemical Engineering, Nanjing University, 22 Hankou Road, Nanjing 210093, China. |
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Abstract: | The infrared spectrum, ultraviolet spectrum, mass spectra, and nuclear magnetic resonance spectra of metoprolol tartrate, an antiarrhythmic medicine, were reported and interpreted comprehensively. The vibrations of functional groups in infrared spectrum, electron transitions in ultraviolet spectrum, and main characteristic fragmentations in mass spectra of metoprolol tartrate were discussed. All the (1) H and (13) C NMR chemical shifts were assigned by means of distoritionless enhancement by polarization transfer-135 and -90, (1) H-(1) H correlation spectroscopy, and (13) C-(1) H correlation spectroscopy via short- and long-range coupling. |
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Keywords: | metoprolol tartrate (MT) infrared spectrum (IR) ultraviolet spectrum (UV) mass spectra (MS) nuclear magnetic resonance (NMR) |
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