城乡队列人群脑卒中发病差异及其影响因素的前瞻性研究

在城市７７８名农村１０３１名队列人群中分别进行了为期１５年及１１年的前瞻性观察。城市组脑萃中平均年标化发病率９５．７／１０万，较农村组１８３．１／１０万明显为低。其发病率差异的主要影响因素除年龄外为农村人群的高嗜酒率、高吸烟率、心电图异常及女性收缩压的增加。另外血胆固醇水平偏低也可能为影响农村脑卒中特别是脑出血高发的因素之一。

A Cohort Study on the Difference of Stroke Incidence between Urban and Rural populations and Related Influential Factors

A longitudinal prospective study was carried out in a cohort of 1 809 persons aged 35 to 74 at entry, including 778 subjects from urban and 1 031 from rural areas. The average annual age-adjusted incidence of stroke was 95. 7/10⁴ in urban group during a 15-year-period from 1979 to 1994, which was significantly lower than that in rural areas (183.1/10⁴) during a 11-year-period from 1983 to 1994. According to the results through multivariate regression analysis and comparative study of risk factors between urban and rural group at baseline examination, it was suggested that in addition to age, factors as drinking habit,smoking, ECG abnormality and elevated systolic blood pressure (in female) were important parameters causing the difference of incidence between urban and rural groups. Other than those factors mentioned above,low level of serum cholesterol in rural population was also suspected as a possible factor positively influencing the development of stroke.