中药治疗对宫颈癌患者预后的影响

目的:通过对宫颈癌患者的临床资料及治疗方案的分析研究,探讨中药治疗是否可以延长宫颈癌患者的生存期。方法:回顾性分析2015年1月-2019年1月1日在辽宁中医药大学附属医院肿瘤科住院治疗并随访到的宫颈癌患者的临床资料。采用单因素及多因素分析分别对患者的确诊时年龄、首诊KPS评分(百分制)、手术、放化疗、中药治疗情况(包括口服中药汤剂时间+中成药治疗情况)等因素进行分析,观察中药治疗是否为宫颈癌患者的独立预后因素,再将患者分为早期(Ⅰ-ⅡA期)组,中期(ⅡB-Ⅲ期)组及晚期(Ⅳ期)组,进一步分析对于不同分期的患者,中药治疗是否可以影响其预后,最后观察中药治疗对Ⅰ-ⅡA期术后的患者及ⅡB-Ⅲ期放疗后的患者生存预后的影响。结果:共收集120例,其中早期患者(Ⅰ-ⅡA期)共60例,早期术后患者53例,中期(ⅡB-Ⅲ期)患者42例,中期放疗后的患者36例,晚期患者(Ⅳ期)18例。单因素及多因素分析显示:中药治疗情况为120例宫颈癌者的预后因素(P<0.05),其中对于ⅡB-Ⅲ期患者的生存预后有明显的影响意义(P<0.05)。结论:中药治疗在一定程度上可延长宫颈癌患者的生存期。

Effect of traditional Chinese Medicine on the Prognosis of Patients with Cervical Cancer

Objective:Based on the analysis of clinical data and treatment options for patients with cervical cancer,it is explored whether traditional Chinese medicine treatment can prolong the survival of patients with cervical cancer.Methods:The clinical data of patients with cervical cancer who were hospitalized and followed up in the Oncology Department of Liaoning University of Traditional Chinese Medicine from January 2015 to January 1,2019 were retrospectively analyzed.Univariate and multivariate analysis were used to analyze the patient’s age at diagnosis,KPS score at the first diagnosis (percentage system),surgery,radiotherapy and chemotherapy,and the treatment of traditional Chinese medicine (including the time of oral Chinese medicine decoction + treatment of proprietary Chinese medicines) and other factors Whether traditional Chinese medicine treatment is an independent prognostic factor for patients with cervical cancer,and the patients are further divided into early (stage Ⅰ-Ⅱ A) group,intermediate (stage Ⅱ B-Ⅲ) group and late (stage Ⅳ) group,and further analysis of the different stages Patients,whether traditional Chinese medicine treatment can affect their prognosis,and finally observe the effect of traditional Chinese medicine treatment on survival prognosis of patients after stage Ⅰ-Ⅱ A and patients after stage Ⅱ B-Ⅲ radiotherapy.Results:A total of 120 cases were collected,of which 60 were early patients (stage Ⅰ-Ⅱ A),53 were early postoperative patients,42 were mid-stage (stage Ⅱ B-Ⅲ) patients,36 were post-radiotherapy patients,and advanced patients were (Phase IV) 18 cases.Univariate and multivariate analysis showed that the prognostic factors of 120 patients with cervical cancer treated with Chinese medicine (P<0.05),which had a significant impact on the survival prognosis of patients with stage Ⅱ B-Ⅲ (P<0.05).Conclusion:Traditional Chinese medicine treatment can prolong the survival of cervical cancer patients to a certain extent.