皮肌炎合并食管黏膜剥脱1例

皮肌炎(dermatomyositis,DM)是一种特发性炎症性肌病,以慢性近端骨骼肌无力、独特的皮肤损害为特征.皮肌炎合并食管黏膜剥脱临床上少见.1例36岁男性患者因"四肢肌肉酸痛、吞咽困难及咽痛"入院,被诊断为DM合并食管黏膜剥脱.患者经过糖皮质激素、免疫抑制剂、针灸及内镜黏膜下剥离术(endoscopic sub...

Dermatomyositis with exfoliation of esophageal mucosa: A case report

Dermatomyositis (DM) is a kind of idiopathic inflammatory myopathy characterized by chronic proximal skeletal muscle weakness and unique skin lesions. However, DM with exfoliation of esophageal mucosa is rare. A 36-year-old male patient complained of muscular soreness of extremities, dysphagia, and pharyngalgia was diagnosed with DM with exfoliation of esophageal mucosa. After treatment with glucocorticoid, immunosuppressant, acupuncture, and endoscopic submucosal dissection (ESD), the above symptoms were disappeared. During the 3-year follow-up period, the results of routine physical examination, laboratory examination, gastroscopy, and imaging examination were normal. High-dose of corticosteroid is needed in the initial treatment, but it must be reduced regularly to avoid adverse reactions. Acupuncture and ESD are also effective as adjuvant therapy.