特定温度模式与小动脉闭塞性缺血性卒中严重程度相关性的研究

目的 探讨寒冷和温暖两种不同温度模式下,气温与小动脉闭塞性缺血性卒中严重程度的相关性.方法 回顾性分析2018年1-12月于苏州大学附属第一医院神经内科住院治疗的小动脉闭塞性缺血性卒中患者的临床资料,记录患者住院当日平均温度、人口学特征、卒中严重程度(NIHSS评分)等资料,评估寒冷和温暖两种不同温度模式下卒中严重程度...

Association between Temperature and Stroke Severity in Patients with Small Artery Occlusion Ischemic Stroke

Objective To investigate the association of the ambient temperature and stroke severity in patients
with small artery occlusion (SAO) ischemic stroke.
Methods The clinical data of SAO ischemic stroke patients who were admitted to Department
of Neurology, the First Affiliated Hospital of Soochow University between January 2018 and
December 2018 were retrospectively analyzed. The average temperatures on the day of admission
were also recorded. The potential risk factors for stroke severity at different temperature mode (cold
and warm) in these patients were analyzed.
Results A total of 361 patients were included, with 179 cases in warm temperature and 182 cases
in cold temperature, 239 cases with minor stroke (NIHSS≤3) and 122 cases with non-minor stroke
(NIHSS>3). The cold temperature was an independent risk factor for stroke severity in SAO subtype
(OR 3.08, 95%CI 1.52-6.24, P =0.002). The heterogeneity test indicated there were interactions
between different risk factors of diabetes mellitus (adjusted OR 3.65, 95%CI 1.14-11.67, P =0.029)
and high-risk hyperlipidaemia (adjusted OR 0.24, 95%CI 0.08-0.68, P =0.008) and temperature. The
independent risk factors for stroke severity in SAO subtype at different temperature mode were also
different.
Conclusions Cold temperature was associated with stroke severity in patients with SAO stroke,
and the risk factors for stroke severity in SAO subtype at different temperature mode were also
different. So the special intervention measures should be made in such patients according to the
ambient temperature.