子宫颈癌术前辅助治疗的规范化

新辅助化疗(neoadjuvant chemotherapy,NACT)是子宫颈.癌术前或放疗前辅助治疗的主要方式,原则上适用于局部晚期(Ⅰ B3～ⅣA期)和部分特殊类型的子宫颈癌患者.顺铂为首选药物,推荐化疗2～3个疗程.肿瘤直径大于4cm的Ⅰ B3～ⅡA2期的子宫颈鳞癌和腺癌的部分患者可以采用新辅助化疗+根治性手术...

Standardization of preoperative adjuvant therapy for cervical cancer.

Neoadjuvant chemotherapy（NACT）is the primary preoperative adjuvant therapy for cervical cancer. In principle，it is suitable for patients with locally advanced cervical cancer（ⅠB3-ⅣA）and some special types of cervical cancer. Cisplatin is the preferred drug，and chemotherapy for 2-3 courses is recommended. Some patients with stage ⅠB3-ⅡA2 cervical squamous cell carcinoma and adenocarcinoma with tumor diameter larger than 4 cm can be treated with radical surgery and pelvic lymphadenectomy after neoadjuvant chemotherapy. For small cell neuroendocrine tumors of the cervix，hysterectomy is performed after neoadjuvant chemotherapy，and then postoperative adjuvant radiotherapy or concurrent chemoradiotherapy is performed，followed by other systemic treatments. It is very important to standardize the application of NACT in preoperative adjuvant treatment of cervical cancer，strictly grasp the indications and contraindications，and give full play to its therapeutic advantages.