清热平喘定哮方对慢性支气管炎患者血清炎性因子及呼吸功能的影响

目的:探讨清热平喘定哮方对慢性支气管炎患者血清炎性因子及呼吸功能的影响。方法:选择2017年3月-2018年2月我院92例慢性支气管炎患者,按随机数字表法分为对照组、观察组,各46例。对照组予以常规治疗,观察组加以清热平喘定哮方治疗,比较两组血清炎性因子及呼吸功能。结果:治疗后,两组CRP、IL-10、TNF-α水平均低于治疗前,且观察组上述指标均低于对照组,差异有统计学意义(t=9.445、8.018、5.095,P=0.000、0.000、0.000);两组FEV1、FVC、FEV1/FVC水平均高于治疗前,且观察组上述指标均高于对照组,差异有统计学意义(t=14.727、7.964、7.430,P=0.000、0.000、0.00);治疗后中医症候积分低于治疗前,且观察组低于对照组,差异有统计学意义(t=4.333,P=0.000)。结论:清热平喘定哮方可有效降低慢性支气管炎患者血清炎性因子水平、中医症候积分,改善其呼吸功能。

Effect of Qingre Pingchuan Dingxiao Recipe on Serum inflammatory Factors and Re spiratory Function in Patients with Chronic Bronchitis

Objective:To investigate the effect of Qingre Pingchuan Dingxiao Recipe on serum inflammatory factors and respiratory function in patients with chronic bronchitis.Methods From March 2017 to February 2018,92 patients with chronic bronchitis in our hospital were selected and divided into a control group and an observation group,each with 46 cases according to the random number table method.The control group was given routine treatment,and the observation group was treated with Qingre Pingchuan Dingxiao Recipe to compare serum inflammatory factors and respiratory function between the two groups.Results After treatment,the levels of CRP,IL-10 and TNF-αin the two groups were lower than before treatment,and the above indicators in the observation group were lower than the control group,the difference was statistically significant(t=9.445,8.018,5.095,P=0.000,0.000,0.000);FEV1,FVC,FEV1/FVC in the two groups were higher than before treatment,and the above indicators in the observation group were higher than the control group,the difference was statistically significant(t=14.727,7.964,7.430,P=0.000,0.000,0.00);after treatment,TCM symptom score is lower than before treatment,and the observation group is lower than the control group,the difference is statistically significant(t=4.333,P=0.000).Conclusion Qingre Pingchuan Dingxiao Recipe can effectively reduce the level of serum inflammatory factors and TCM symptom scores in patients with chronic bronchitis and improve their respiratory function.