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暖宫止痛汤治疗寒凝血瘀型原发性痛经的临床观察
引用本文:谢雅贞,钱建强,陆启滨.暖宫止痛汤治疗寒凝血瘀型原发性痛经的临床观察[J].中医药临床杂志,2020(3):519-522.
作者姓名:谢雅贞  钱建强  陆启滨
作者单位:江苏省太仓市中医医院;江苏省中医院
基金项目:太仓市科技局应用基础研究计划项目:暖宫止痛汤治疗原发性痛经的临床及实验研究(TC2017YYJC03)。
摘    要:目的:观察暖宫止痛汤治疗寒凝血瘀型原发性痛经的临床疗效。方法:将符合标准的60例寒凝血瘀型原发性痛经患者随机分成2组,治疗组30例服用暖宫止痛汤;对照组30例服用月月舒颗粒。2组均以1个月经周期为1个疗程,连续治疗3个疗程后评价疗效。结果:治疗组痊愈17例,有效11例,无效2例,总有效率为93.33%;对照组痊愈11例,有效13例,无效6例,总有效率为80%。2组比较,有显著性差异 (P<0.05)。暖宫止痛汤在减少中医证候积分,改善患者痛经方面优于对照组(P<0.05);暖宫止痛汤在降低患者血清中的PGE2、PGF2α的疗效优于对照组(P<0.05)。暖宫止痛汤停药3个月经周期远期疗效总有效率93.33%,对照组远期疗效总有效率66.67%,暖宫止痛汤远期疗效优于月月舒(P<0.05)。结论:暖宫止痛汤治疗寒凝血瘀型原发性痛经的疗效优于月月舒颗粒。

关 键 词:原发性痛经  治疗  寒凝血瘀型  暖宫止痛汤  临床观察

Clinical Observation on Treatment of Primary Dysmenorrhea Caused by Congealing Cold and Blood Stasis with Nuangong Zhitong Decoction
XIE Yazhen,QIAN Jianqiang,LU Qibin.Clinical Observation on Treatment of Primary Dysmenorrhea Caused by Congealing Cold and Blood Stasis with Nuangong Zhitong Decoction[J].Clinical journal of traditional chinese medicine,2020(3):519-522.
Authors:XIE Yazhen  QIAN Jianqiang  LU Qibin
Institution:(Taicang TCM Hospital Affiliated to Nanjing University of Chinese Medicine Jiangsu Taicang 215400,China;The Affiliated Hospital of Nanjing University of Chinese Medicine Jiangsu Nanjing 210029,China)
Abstract:Objective:To observe the clinical efficacy of Nuangong Zhitong decoction in treating primary dysmenorrhea of cold coagulation and stasis type.Methods:60 patients with primary dysmenorrhea of cold coagulation and stasis type were randomly divided into two groups,30 patients in the treatment group were treated with Nuangong Zhitong decoction;30 patients in the control group were treated with Yue Yue Shu Granules.Both groups took 1 menstrual cycle as a course of treatment,and the efficacy was evaluated after 3 consecutive courses of treatment.Results:17 cases were cured in the treatment group,11 cases were effective,2 cases were ineffective,and the total effective rate was 93.33%;11 cases were cured in the control group,13 cases were effective,6 cases were ineffective,and the total effective rate was 80%.There was a significant difference between the two groups (P<0.05).Nuan Gong Zhi Tong Decoction is superior to the control group in reducing TCM syndrome scores and improving dysmenorrhea in patients (P<0.05);Nuan Gong Zhi Tong Decoction is superior to the control group in reducing PGE2 and PGF2α in patients’ serum (P<0.05).The total effective rate of long-term efficacy of Nuangong Zhitong decoction was 39.3% after stopping 3 months of menstrual cycle,and the total effective rate of long-term effect of control group was 66.67%.Conclusion:Nuangong Zhitong decoction is better than Yueyueshu Granules in treating primary dysmenorrhea of cold coagulation and stasis type.
Keywords:Primary dysmenorrhea  Treatment  Congealing cold and blood stasis  Nuangong Zhitong decoction  Clinical observation
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