| 高效液相色谱法测定复方阿司匹林片剂的含量 |
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| 引用本文： | 王晓燕,崔福德,马汝敏. 高效液相色谱法测定复方阿司匹林片剂的含量[J]. 沈阳药科大学学报, 2002, 19(1): 31-34 |
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| 作者姓名： | 王晓燕 崔福德 马汝敏 |
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| 作者单位： | 1. 沈阳药科大学药学院,辽宁,沈阳,110016
2. 青海制药厂,青海,西宁,810003 |
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| 摘 要： | 目的建立复方阿司匹林片剂的含量测定方法。方法采用高效液相色谱法。结果阿司匹林0 4～ 5 2mg/mL呈线性 ,平均回收率为 1 0 0 2 % (RSD =0 6 7% ,n =9) ;磷酸可待因 0 0 0 8～0 1 0 4mg/mL呈线性 ,平均回收率为 98 7% (RSD =2 2 1 % ,n =9)。结论适用于复方阿司匹林片剂的含量测定。
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| 关 键 词： | 复方阿司匹林片 高效液相色谱法 阿司匹林 磷酸可待因 含量测定 |
| 文章编号： | 1006-2858(2002)01-0031-04 |
| 修稿时间： | 2001-06-20 |
Determination of the contents of the compound aspirin tablets by HPLC |
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| WANG Xiao yan,CUI Fu de,MA Ru min. Determination of the contents of the compound aspirin tablets by HPLC[J]. Journal of Shenyang Pharmaceutical University, 2002, 19(1): 31-34 |
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| Authors: | WANG Xiao yan CUI Fu de MA Ru min |
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| Abstract: | Objective To establish a method for determination of the content of compound aspirin tablets.Method The content of compound aspirin tablets was determined by HPLC mathod. Results The linear relationship between the concentration and absorption value were established in the rang of 0 4～5 2 mg/mL for aspirin and in the range of 0 008～0 104 mg/mL for codeine phosphate.The average recovery of aspirin was 100 2% (RSD=1 6, n =9) and the average recovery of codeine phosphate was 98 7%( RSD= 2 21%, n =9).Conclusions The results demonstrated that this method was simple,rapid and reliable. |
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| Keywords: | compound aspirin tablet aspirin codeine phosphate HPLC determination of content |
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