首页 | 本学科首页   官方微博 | 高级检索  
     


An automated method for studying exploratory and stereotyped behaviour in rats
Authors:Roger O. A. Makanjuola  Graham Hill  Ian Maben  Ronald C. Dow  George W. Ashcroft
Affiliation:(1) MRC Brain Metabolism Unit, University Department of Pharmacology, 1 George Square, EH8 9JZ Edinburgh, U.K.
Abstract:A technique is described for studying exploratory as well as stereotyped behaviour in rats using an automated hole-board. Both visual and automated recordings can be employed using the technique. Hole dipping is monitored automatically using an infra-red detector system. Repetitive patterns of hole-dipping are used as parameters of stereotyped behaviour while the more random patterns of hole-dipping are used as parameters of exploration.There was a high significant correlation between the records of hole-dipping behaviour as recorded visually and automatically. There was also a high significant correlation between the measures of repetitiveness/randomness of hole-dipping behaviour from automatic and visual recordings. The pattern and levels of hole-dipping conformed with expectations both as regards changes with time and with increasing doses of dl-amphetamine.
Keywords:Rat  Exploratory behaviour  Stereotyped behaviour  Hole-board  dl-Amphetamine
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号