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Cytochrome P450 2E1 RsaI/PstI and DraI polymorphisms are risk factors for lung cancer in Mongolian and Han population in inner Mongolia |
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| Authors: | Xiu-lan Su Ba Bin Hong-wei Cui Mei-rong Ran |
| Affiliation: | Xiu-lan Su1**,Ba Bin2*,Hong-wei Cui1,Mei-rong Ran1 1Clinical Medical Center,Affiliated Hospital,Inner Mongolian Medical College,Hohhot 010050,China,2Department of Internal Medicine,Medical Emergency Center of Kangbashi New Direct,Erdos City,Inner Mongolia |
| Abstract: | Objective: To explore the relationship between cytochrome P450 2E1 (CYP2E1) RsaI/PstI and DraI polymorphism and lung cancer susceptibility in Mongolian and Han population in Inner Mongolia of China. Methods: CYP2E1 RsaI/PstI and DraI polymorphisms were detected by polymerase chain reaction-restriction fragment length polymorphism in 64 lung cancer patients, 150 healthy Mongolian and 150 healthy Han individuals. The distribution of genotype and allele frequencies of CYP2E1 RsaI/PstI and DraI polymorphisms we... |
| Keywords: | Cytochrome p450 2E1 Gene polymorphism Lung cancer Susceptivity |
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