| 乌梅及其不同炮制品的药理作用比较 |
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| 引用本文： | 王璐,张红宇,王莉.乌梅及其不同炮制品的药理作用比较[J].中药材,2010(3). |
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| 作者姓名： | 王璐 张红宇 王莉 |
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| 作者单位： | 云南省食品药品检验所; |
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| 摘 要： | 目的:比较乌梅及其炮制品乌梅肉、乌梅炭的药理作用的异同;研究乌梅中有机酸含量较高的苹果酸、枸橼酸与乌梅药理作用的关系。方法:通过炭末法小鼠小肠推进运动试验,小鼠眼眶静脉丛取血测定血糖值及试管法体外抗菌试验,对乌梅、乌梅肉、乌梅炭、苹果酸、枸橼酸进行药理作用研究。结果:乌梅、乌梅炭、乌梅肉、苹果酸均能明显提高小鼠小肠碳末推进百分率;乌梅炭、乌梅肉、苹果酸、枸橼酸可使正常小鼠血糖降低;乌梅、乌梅炭、乌梅肉、苹果酸、枸橼酸对金黄色葡萄球菌、大肠杆菌、绿脓杆菌、白色念珠菌有不同程度的抑菌作用。结论:乌梅及其炮制品的药理作用不尽相同,为保证临床用药的准确性和安全性,建议乌梅及其炮制品应对症入药。乌梅中有机酸含量较高的苹果酸、枸橼酸与乌梅药理作用关系密切,可将其列入乌梅及其制剂质量标准控制的项目。
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| 关 键 词： | 乌梅 血糖 小肠推进 抑菌 |
Comparison of Pharmacological Effects of Fructus Mume and Its Processed Products |
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| WANG Lu,ZHANG Hong-yu,WANG Li.Comparison of Pharmacological Effects of Fructus Mume and Its Processed Products[J].Jorunal of Chinese Medicinal Materials,2010(3). |
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| Authors: | WANG Lu ZHANG Hong-yu WANG Li |
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| Institution: | WANG Lu,ZHANG Hong-yu,WANG Li (Yun Nan Institute for Food , Drug Control,Kunming 650031,China) |
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| Abstract: | Objective:To compare the pharmacological effects of Fructus Mume and its processed products,to investigate pharmacologic relation among Fructus Mume,malic acid,citric acid.Methods:Blood glucose from orbital sinus was measured to observe the effects of Fructus Mume,Fructus Mume sarcocarp and Fructus Mume carbon,malic acid,citric acid on blood glucose level of normal mice.The efficacy of drugs above on gastrointestinal motility was investigated through coated charcoal method in small intestinal propulsive mot... |
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| Keywords: | Fructus Mume Blood glucose Small intestinal propulsion Antibacterial action |
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