| 替罗非班用于老年急性冠状动脉综合征患者经皮介入治疗临床观察 |
| |
| 引用本文： | 田磊,米树华,戴文龙,张晓霞,苏工,赵全明. 替罗非班用于老年急性冠状动脉综合征患者经皮介入治疗临床观察[J]. 实用诊断与治疗杂志, 2009, 23(8) |
| |
| 作者姓名： | 田磊 米树华 戴文龙 张晓霞 苏工 赵全明 |
| |
| 作者单位： | 首都医科大学附属北京安贞医院特需医疗科,北京市,100029 |
| |
| 摘 要： | 目的:评价替罗非班用于老年急性冠状动脉综合征患者经皮介入治疗的临床疗效和安全性。方法:选择符合冠心病入选标准并拟行经皮介入治疗的患者106例,同时接受阿司匹林、氯吡格雷及肝素治疗。52例患者于植入药物涂层支架前给予替罗非班负荷量后以维持量持续静脉泵入36 h者为替罗非班治疗组;另54例患者为对照组。分别于术后36 h和30 d评价2组患者主要终点事件的联合发生率,观察有无严重出血、监测血小板聚集率及血小板计数等。结果:与对照组比较,替罗非班组血管成形术后36 h复合终点事件发生率低(P<0.05);30 d内替罗非班组复合终点事件发生率明显降低(P<0.01);替罗非班维持期间,血小板聚集率明显下降(P<0.01)。无严重出血、血小板减少等严重并发症发生。结论:替罗非班用于老年急性冠状动脉综合征患者的经皮介入治疗安全、有效。
|
| 关 键 词： | 急性冠状动脉综合征 替罗非班 受体拮抗剂 终点事件 |
Clinical effects of tirofiban in elderly patients with acute coronary syndrome by percutaneous coronary intervention |
| |
| TIAN Lei,MI Shuhua,DAI Wenlong,et al.. Clinical effects of tirofiban in elderly patients with acute coronary syndrome by percutaneous coronary intervention[J]. Journal of Practical Diagnosis and Therapy, 2009, 23(8) |
| |
| Authors: | TIAN Lei MI Shuhua DAI Wenlong et al. |
| |
| Affiliation: | TIAN Lei,MI Shuhua,DAI Wenlong,et al.Beijing Anzhen Hospital of the Capital University of Medical Sciences,Beijing 100029,China |
| |
| Abstract: | Objective To evaluate the efficacy and safety of tirofiban in elderly patients with acute coronary syndrome by percutaneous coronary intervention.Methods One hundred and six in-patients with acute coronary syndrome receiving percutaneous coronary intervention were divided into group of tirofiban(n=52) and control group(n=54).All patients received intravenous heparin,oral aspirin and clopidogrel.The group of tirofiban was given loading dose of tirofiban and maintenance dose for 36 hours before the implantati... |
| |
| Keywords: | |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
