临床标本中真菌分离及药敏结果分析

目的调查目前我院临床标本中真菌感染现状及耐药性情况.方法各种临床标本经常规方法分离培养,用法国生物-梅里埃API 20C AUX鉴定系统鉴定,并用K-B法进行药敏试验.结果从3 260份临床标本中分离出真菌476株28种,其中前3位为白色念珠菌64.7%,热带念珠菌12.4%,光滑念珠菌3.78%,检出真菌最多的部位是呼吸道,占真菌标本的68.1%,以白色念珠菌为主.结论真菌感染在临床上显上升趋势且产生了耐药株,重视真菌的培养鉴定和药敏试验,以指导临床合理选择抗真菌药物.

Fungus Culture and Antifungal Sensitivity: Analysis of Clinical Samples

OBJECTIVE To investigate the characteristics of fungus infection and antifungal resistance at the Southwest Hospital,Chongqing. METHODS The fungi were cultured with general method,isolated and identified with API 20C AUX identification system.The antifungal sensitivity was detected with the K-B mothod. RESULTS A total of 476 strains of fungi were isolated from 3 260 clinical samples.There were 28 species of fungi having been identified all together.and the first three were Candida albicans (64.7%), C.tropicalis (12.4%), and (C.glabrata) (3.78%). Respiratory system infection was the most common fungal infection, accounted for 68.1%. C. albicans was still of the main one. CONCLUSIONS Fungus infection rate is raising gradually and the antifungal resistant strains are found from time to time.In order to guide clinically the selection of the reasonable antifungals,the isolation and the antifungal sensitivity tests should also be stressed.