| 大鼠失神经骨折愈合中骨痂体积与生物力学强度的相关性分析 |
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| 引用本文： | 王小健,杜志强,苏云星,吴变梅. 大鼠失神经骨折愈合中骨痂体积与生物力学强度的相关性分析[J]. 山西医科大学学报, 2008, 39(3): 226-230 |
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| 作者姓名： | 王小健 杜志强 苏云星 吴变梅 |
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| 作者单位： | 1. 山西省人民医院骨科,太原,030012
2. 山西省孝义市下堡中心医院骨科 |
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| 摘 要： | 目的 探讨失神经骨折愈合中病理性骨痂的体积与力学强度的相关性.方法 Wistar大鼠90只随机分为3组,每组30只:运动神经(前根)切断组、感觉神经(后根)切断组、前后根切断组,均选择性切断一侧L4-L6神经根.所有大鼠于神经根切断侧胫骨造成横行骨折,髓钉固定.30 d后取大鼠患侧胫骨,测胫骨近端骨密度、胫骨湿重称量、在X线片上测量骨痂宽度、胫骨进行生物力学拉伸测试,SPSS统计数据.结果 患侧胫骨近端骨密度三组间比较无统计学差异(P>0.05),病理性骨痂其体积与生物力学强度呈负相关(P<0.05),以涉及感觉神经(后根)损伤组尤甚(P<0.05).结论 失神经骨折愈合中所形成的病理性骨痂其体积与生物力学强度呈负相关,感觉神经纤维对骨折愈合的影响较运动神经纤维显著.
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| 关 键 词： | 骨折愈合 失神经 骨痂 生物力学强度 大鼠 失神经 骨折愈合 骨痂 体积 生物力学强度 相关性分析 rats fracture healing callus bony pathological mechanical properties volume 运动 影响 神经纤维 损伤 负相关 统计学差异 |
| 文章编号： | 1007-6611(2008)03-0226-04 |
| 修稿时间： | 2007-10-24 |
Correlation between the volume and the mechanical properties of pathological bony callus in fracture healing of denervated rats |
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| WANG Xiao-jian,DU Zhi-qiang,SU Yun-xing,WU Bian-mei. Correlation between the volume and the mechanical properties of pathological bony callus in fracture healing of denervated rats[J]. Journal of Shanxi Medical University, 2008, 39(3): 226-230 |
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| Authors: | WANG Xiao-jian DU Zhi-qiang SU Yun-xing WU Bian-mei |
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| Affiliation: | 1Dept of Orthopaedics;Shanxi Provincial People's Hospital;Taiyuan 030012;China;2Dept of Orthopaedics;Xiabao Central Hospital of Xiaoyi City |
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| Abstract: | Objective To explore the correlation between the volume and the mechanical properties of pathological bony callus of denervated fracture healing.Methods Ninety Wistar rats were randomly divided into three groups:anterior rhizotomy group(ART,n=30),posterior rhizotomy group(PRT,n=30)and radicotomy group(RT,n=30).Tibial transverse fracture of all rats were made at nerve-cut side and then fixed with intramedullary nail.At the fracture-tibia side,the rats were inflicted with the selective radicotomy from L4 to L... |
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| Keywords: | fracture healing denervation bony callus mechanical property |
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