老年慢性阻塞性肺疾病急性加重期血清降钙素原／C-反应蛋白检测的临床意义

目的探讨血清降钙素原（PCT）与C-反应蛋白（CRP）在老年慢性阻塞性肺疾病（COPD）急性加重期水平发生变化的临床意义。方法测定52例老年COPD急性加重期、50例健康对照组研究对象的血清PCT、CRP指标,并比较临床治疗前后老年COPD患者两项指标水平变化情况。结果老年COPD急性加重期患者血清PCT（5.871.01）和CRP（39.647.15）水平高于健康对照组PCT（0.340.12）和CRP（1.510.16）,差异有统计学意义（P〈0.01）;临床治疗后老年COPD患者病情得到缓解,PCT和CRP水平下降;老年COPD急性加重期两项指标阳性检出率高（P〈0.05）。结论血清TCT、CRP是反映老年COPD急性加重期的辅助诊断指标。

The clinical implications of serum procalcitonin and high-sensitivity C-reactive protein in elderly acute exacerbations of chronic obstructive pulmonary disease

Objective To explore serum calcitonin original （PCT）and C-reactive protein （CRP）in the elderly with chronic obstructive pulmonary disease （COPD）in acute aggravating period level change of clinical significance.Methods Determination of 52 cases of senile COPD exacerbations stage,50 cases of healthy controls the object of study of ser-um PCT and CRP,and compare the clinical treatment in elderly patients with COPD before and after two indicators lev-el changes.Results Senile COPD patients with acute aggravating period of serum PCT （5.871.01）and CRP（39.647. 15）levels higher than that of healthy controls’s PCT（0.340.12）and CRP（1.510.16）,The difference was statistically significant（P 〈0.01）;After clinical treatment in elderly patients with COPD disease ease,PCT and CRP levels drop, Senile COPD exacerbations period two indicators positive detection rate is high（P 〈0.05）.Conclusion Serum TCT, CRP reflects elderly acute aggravating period of COPD auxiliary diagnostic indicators.