| 艾滋病合并耶氏肺孢子虫(菌)肺炎的实验室诊断 |
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| 引用本文： | 陈敬捷,李勇,何晗,苏凌松,秦松树,胡宏波,唐柳生,李世立. 艾滋病合并耶氏肺孢子虫(菌)肺炎的实验室诊断[J]. 中国寄生虫学与寄生虫病杂志, 2011, 0(3) |
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| 作者姓名： | 陈敬捷 李勇 何晗 苏凌松 秦松树 胡宏波 唐柳生 李世立 |
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| 作者单位： | 广西壮族自治区龙潭医院检验科;广西壮族自治区龙潭医院艾滋病科;柳州市肿瘤医院检验科;柳州市柳铁中心医院检验科; |
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| 基金项目： | 国家十一五科技重大专项(No.2008ZX10005-003); 广西卫生厅计划科研项目(No.Z2007030)~~ |
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| 摘 要： | 采用吉氏染色法检查艾滋病患者有耶氏肺孢子虫(菌)肺炎临床表现者痰液和支气管肺泡灌洗液(BALF)中的耶氏肺孢子虫(菌)。抽取部分留痰患者(500例)血液,检测CD4+淋巴细胞。结果显示,痰液标本耶氏肺孢子虫(菌)的阳性率(46.8%,845/1 806)显著低于BALF标本(55.8%,106/190)(P<0.05)。耶氏肺孢子虫(菌)阳性患者有临床症状的比例(96.6%,816/845)显著高于阴性者(64.0%,615/961)(P<0.05)。患者血液中CD4+淋巴细胞数量越少,耶氏肺孢子虫(菌)阳性率越高,CD4+细胞数量>200×106/L组、200×106/L～100×106/L组和<100×106/L组的耶氏肺孢子虫(菌)阳性率分别为12.0%(6/50)、39.0%(39/100)和54.6%(191/350)(P<0.05)。吉氏染色法是较好的检查耶氏肺孢子虫(菌)的方法,简单易行,容易推广,但需积累经验。
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| 关 键 词： | 艾滋病 耶氏肺孢子虫(菌) 吉氏染色 支气管肺泡灌洗液 CD4 淋巴细胞 |
Laboratory Diagnosis of HIV/AIDS Patients Complicated with Pneumocystis jirovecii Poneumonia |
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| CHEN Jing-jie,LI Yong,HE Han,SU Ling-song,QIN Song-shu,HU Hong-bo ,TANG Liu-sheng,LI Shi-li. Laboratory Diagnosis of HIV/AIDS Patients Complicated with Pneumocystis jirovecii Poneumonia[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2011, 0(3) |
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| Authors: | CHEN Jing-jie LI Yong HE Han SU Ling-song QIN Song-shu HU Hong-bo TANG Liu-sheng LI Shi-li |
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| Affiliation: | CHEN Jing-jie1,LI Yong2,HE Han1,SU Ling-song2,QIN Song-shu3,HU Hong-bo4 *,TANG Liu-sheng1,LI Shi-li1(1 Department of Clinical Laboratory,Longtan Hospital,Liuzhou 545005,China,2 Department of HIV/AIDS,3 Department of Clinical Laboratory,Tumor Hospital of Liuzhou City,Liuzhou 545002,4 Department of Clinical Laboratory,Liuzhou Railway Center Hos-pital,Liuzhou 545006,China) |
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| Abstract: | Pneumocystis jirovecii was detected in sputum samples and bronchoalveolar lavage fluid(BALF) ob-tained from HIV/AIDS patients complicated with Pneumocystis jirovecii poneumonia by Giemsa staining.CD4+ T lymphocytes of 500 patients were counted by flow cytometer.P.jirovecii positive rate in sputum samples(46.8%,845/1 806) was significantly lower than that of BALF(55.8%,106/190)(P<0.05).The proportion of patients developing clinical symptoms in P.jirovecii positive cases(96.6%,816/845) was higher than that of... |
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| Keywords: | AIDS Pneumocystis jirovecii Giemsa staining BALF CD4 lymphocyte |
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