中晚期胃癌中医辨证分型与组织病理学分型的关系及疗效观察

目的 :分析中晚期胃癌术后中医辨证分型与组织病理学分型之关系并观察各型疗效。 方法 :对中晚期胃癌 ,进行术前辨证分型 ,术后化疗合并中药治疗 ,随访观察。 结果 :脾胃虚寒型、肝胃不和型 ,其中腺癌占绝大多数 ,且生存率高 ,3年和 5年生存率分别为 81 3% (13/ 16 )、6 8 8% (11/ 16 ) ,81 8% (9/ 11)、72 7% (8/ 11) ,经统计学处理有显著差异 ,P <0 .0 5。气血双亏、气滞血瘀两型 ,低分化腺癌较多。脾肾阳虚型 3年、5年生存率均为 0。 结论 :中晚期胃癌应积极采取综合治疗 ,以达到改善肿瘤患者生活质量 ,提高远期疗效的目的。

The Relation between the Classification of Syndrome Differentiation on Traditional Chinese Medicine and Histopathology Classification in Moderate late Stage of Gastric Carcinoma and the Therapeutic Evaluation

Objective:To analyze the relations between the classification of syndrome differentiation on traditional Chinese medicine and histopathology classifications in moderate late stage of postoperative gastric carcinoma and observe the therapeutic effects of each type.Methods:The patients with moderate late stage of gastric carcinoma are classified by the syndrome differentiation preoperatively,received combined chemotherapy and Chinese herbs treatment,Followed up closely and got the observed results.Results:Most carcinoma of the type of defficiency of spleen yang and the type of incoordination between the liver and the stomach qi stagnation are adenocarcinoma,which have higher survival rate:3,5 years survival rate are 81.3%(13/16);68.8%(11/16);68.8%(11/16);81.8%(9/11);72.8%(8/11)respectively.The differences are significant statistically.There are more low differentiated adenocarcinomas in the type of deficiency of both qi and blood and the type of qi stagnation and blood stasis.The 3,5 years survival rate of the type of deffiency of both spleen and the kidney are 0.Conclusion:The patients with moderate late stage of gastric carcinoma should receive combined treatments to improve the life quality and forward therapeutic effects.