酒精中毒致视网膜色素上皮损伤观察

目的 观察急慢笥酒精中毒后视网膜色素上皮损伤情况。方法 对９例（１８眼）急慢性酒精中毒患者进行了眼底荧光血管造影（ＦＦＡ）及视觉电生理（ＥＲＧ，ＶＥＰ）检查。结果 ２例（４眼）急性酒精中毒者经药物治疗后视力完全恢复，１例（２眼０ＦＦＡ见双眼底视网膜色素上皮弥漫性损伤。慢性酒精中毒６例１２眼经药物后ＦＦＡ为双眼底视风纱上皮炎改变，ＥＲＧ，ＶＥＰ无好转。结论 急性酒精中毒引起的眼部改变大多时恢复，慢性

Damage of retinal pigment epithelium caused by alcoholism

Objective To observe the damage of retinal pigment epithelium(RPE)caused by acute or chronic alcoholism. Methods 9 cases(18 eyes)of alcoholism were examined by fundus fluorescein angiography(FFA),electroretinography(ERG)and visual evoked potential(VEP). Results The visual acuity completely recovered by drugs in 2 cases(4 eyes) of acute alcoholism.The FFA,ERG and VEP showed normal in the follow up periods.But the FFA changes in 1 cases(2 eyes)after acute alcoholism showed a diffusive intensive fluorescence background in whole fundus with black isolated pigment spots and marked pigment accumulation and loss in macular area.The visual acuity improved little by drugs in 6 cases(12 eyes)of chronic alcoholism.The FFA indicated an intensive unhomogeneous fluorescence stains in RPE and high fluorescence spots in macula area. Conclusion The ocular fundus damage caused by acute alcoholism recoverd in most cases.The functional and organic damage of the retina and macula were seen by chronic alcoholism.FFA,ERG and VEP can objectively reflect the degree and prognosis of RPE damage caused by alcoholism.