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基于有限元的组织工程肌腱支架材料的力学分析
引用本文:周彬,李宏,余毅勤,崔磊,曹谊林. 基于有限元的组织工程肌腱支架材料的力学分析[J]. 组织工程与重建外科, 2006, 2(2): 86-87. DOI: 10.3969/j.issn.1673-0364.a081
作者姓名:周彬  李宏  余毅勤  崔磊  曹谊林
作者单位:上海国睿生命科技有限公司;华东理工大学
摘    要:目的 对组织工程生物可降解支架材料进行力学分析.方法 建立了一种组织工程肌腱支架材料的三维模型,用有限元数值分析方法,对所建模型在不同载荷情况下的受力状况进行了计算分析.结果 相对于该材料表面的狭长槽而言,最大应力发生在狭长槽两端面的上方的两个角.该材料在所加力大于0.01牛时产生明显变形,当拉力达到0.05牛顿时已超过材料的力学承受极限.结论 有限元的分析方法是合理、可行的,对细胞如何在材料的分布提供理论依据.

关 键 词:组织工程  支架材料  有限元法  
修稿时间:2006-02-14

The Mechanical Analysis Of Scaffold For Tendon Tissue Engineering Using Finite Elements Method
ZHOU Bin,LI Hong,YU Yiqin,CUI Lei,CAO Yi-lin. The Mechanical Analysis Of Scaffold For Tendon Tissue Engineering Using Finite Elements Method[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2006, 2(2): 86-87. DOI: 10.3969/j.issn.1673-0364.a081
Authors:ZHOU Bin  LI Hong  YU Yiqin  CUI Lei  CAO Yi-lin
Abstract:Objective Make mechanical analysis on the tissue engineering scaffold. Method In this paper, a 3D model simulating a kind of scaffold for tissue engineered tendon is established using finite element method. We delivered sufficient computation and analysis to the model under all kinds of forces possible. Results To that kind of model with long and narrow slots parallel to each other on its surface, the maximal stress occurred in the top corners of the bicephalous planes. When a force up to 0.01 Newton was added, we observed obvious transfiguration, and the model witnessed a collapse under the force up to 0.05 Newton. Conclusion It's reasonable and feasible to use FEM analysis in order to give some supports in theory in the aspect of how cells distribute on the scaffold.
Keywords:Tissue Engineering  Scaffolds  Finite element method (FEM)
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