不同年龄组急性心肌梗死溶栓疗效的比较

目的:探讨不同年龄急性心肌梗死(AMI)患者溶栓治疗的有效性和安全性。方法:将172例AMI患者按年龄段分成青年组(<45岁,21例)、中年组(45-59岁,103例)、老年组(≥60岁,48例)共3组,比较其临床结果。结果:青年组、中年组、老年组比较,血管再通率分别为66.7%、61.2%、60.4%,(P>0.5);4周病死率分别为9.5%、10.7%、12.5%(P>0.5);出血并发症分别为0、16.5%、33.3%(P<0.01);老年组血管再通者与血管未通者比较病死率分别为3.4％及26.3％(P

Thrombolytic therapy for patients with acute myocardial infarction in various age groups

Objective To explore the efficacy and safety of thrombolytic therapy in different ages with acute myocardial infarc-tion(AMI). Method 172 patients with AMI were divided into 3 groups: young group(aged<45 years,n=21);pre-elderly group(aged: 45-59 years,n=103);elderly group (aged≥60 years,n=48)to observe clinical outcomes of the thrombolytic therapy.Results The clinical repatency rate was 61.9% in young group, 61.2% in pre-elderly group and 60.4% in elderly group(P>0.5);The mortality within four weeks was 9.5%a0.7%,12.5%(P>0.5)and various major complications was 0,16.5%,33.3%(P<0.01). The four weeks mortality of elderly group with and without repatency were 3.4% and 26.3%(P<0.01). Conclusion The efficacy of thrombolytic therapy has no relationship with patient's age.but is closely related with repatency of related coronary artery,so the thrombolytic therapy is beneficial during the treatment of aged patients with AMI rather than dangerous.