| 不同产地黄连的体外抑菌活性与镇静作用 |
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| 引用本文： | 陈淑清,陈淑杰,刘卫建,周群英,方忻平,帅红,谢成科.不同产地黄连的体外抑菌活性与镇静作用[J].华西药学杂志,1990(3). |
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| 作者姓名： | 陈淑清 陈淑杰 刘卫建 周群英 方忻平 帅红 谢成科 |
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| 作者单位： | 华西医科大学药学院药理教研室 成都
(陈淑清，陈淑杰，周群英)，西藏自治区医院 拉萨
(刘卫建)，华西医科大学药学院生药教研室 成都
(方忻平，帅红)，华西医科大学药学院生药教研室 成都(谢成科) |
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| 摘 要： | 本文比较了不同产地的7种黄连与小檗碱的体外抑菌活性及镇静作用。体外抑菌活性表明,黄连5mg/ml与小檗碱0.5mg/ml比较,除四川巫山及四川石柱黄连外,其它均优于小檗碱。镇静作用表明,各种黄连及小檗碱与生理盐水比较,均有显著差异(p<0.05)而与小檗碱比较无显著差异。
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| 关 键 词： | 黄连 小檗碱 最低抑菌浓度 镇静作用 |
COMPARISON OF IN VITRO BACTERIOSTATIC AND SEDATIVE ACTIONS OF RHIZOMA COPTIDIS FROM DIFFERENT AREAS |
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| Chen Shuqing,Chen Shujie,Liu Weijian,Zhou Qunying,Fang Xinping,Shuai Hong,Xie Chenko.COMPARISON OF IN VITRO BACTERIOSTATIC AND SEDATIVE ACTIONS OF RHIZOMA COPTIDIS FROM DIFFERENT AREAS[J].West China Journal of Pharmaceutical Sciences,1990(3). |
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| Authors: | Chen Shuqing Chen Shujie Liu Weijian Zhou Qunying Fang Xinping Shuai Hong Xie Chenko |
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| Institution: | Chen Shuqing,Chen Shujie,Liu Weijian,Zhou Qunying,Fang Xinping,Shuai Hong,Xie Chenko Department of Pharmacology,School of Pharmacy,WCUMS Department of Pharmacognosy,School of Pharmacy,WCUMS |
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| Abstract: | We have compared the
in vitro bacteriostatic and sedative acti-
ons of seven Rhizoma coptidises from
different areas and Berberine. It was
found that majority of Rhizoma coptidises
(5mg/ml) except drugs No. 6 and No. 7
are more effective than Berberine(0.5mg
/ml) in vitro bacteriostatic test. AII
Rhizoma ceptidises and Berberine could
significantly decrease the spontaneous
activities of mice (p<0.01, as compared
with control) , but the difference be-
tween Rhizoma coptidises and Berberine
was not significant. |
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| Keywords: | Rhizoma coptidis Berberine Minimum inhibitory concentration (MIC) Sedative action |
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