耐甲氧西林金黄色葡萄球菌分布及耐药性分析

目的 了解我院耐甲氧西林金黄色葡萄球菌(MRSA)的临床分布和耐药情况.方法 采用VITEK-2全自动微生物分析仪和WHONET软件,对我院2008年-加10年从临床分离的1401株耐甲氧西林金黄色葡萄球的分布及耐药情况进行回顾性分析.结果 3年内共分离出MRSA 1401株,其中以痰标本为主,占78.5%,其次是伤口...

Distribution of Methicillin-resistant Staphylococcus aureus and drug resistance

Objective To analyze the methicillin-resistant Staphylococcus aureus(MRSA)clinical distribution and drug resistance in our hospital.Methods By VITEK-2 automated microbiological analyzer and WHONET software,retrospectively analyze the distribution and drug resistance of 1401 clinical isolates of methicillin-resistant Staphylococcus aureus from 2008-2010 in our hospital.Results Isolated MRSA 1401 strain in 3 years,sputum samples which mainly,accounting for 78.5%,followed was secretion and blood;Higher detection rate was Neurology departments,account for 319(22.8%).The resistance rate of MRSA was deteced,Gentamicin,Clindamycin and Erythromycin resistance rate were very high,more than 80.0% in 3 year.Ciprofloxacin resistance rate remained at a high level of 95.0%.Tetracycline resistance rate had declined,from 2008 to 80.0% declining to 67.9% in 2010.Cotrimoxazole resistance rate of 35.4% from 2008 up to 47.2% in 2010.They had not been found resistant to Vancomycin,Teicoplanin and Linezolid for MRSA.Conclusion MRSA was multi-drug resistance,and drug resistance was very serious.MRSA surveillance should be strengthened,in order to provide the basis for rational clinical use of antibiotics.